DNemulator is a package for simulating DNA sequencing errors,
polymorphisms, cytosine methylation and bisulfite conversion.
- Simulate polymorphisms based on real polymorphisms and their
- Simulate diploid genomes
- Simulate sequencing errors based on real per-sequence, per-base
- Simulate various cytosine methylation rates depending on
cg-context, and bisulfite conversion
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The bisulfite alignment benchmark provides an
example of using DNemulator.
can also simulate bisulfite sequencing experiments. DNemulator can do
some things that Sherman cannot, and vice-versa.
Benchmark, using real (not simulated) data. This is obviously
more realistic, but it has the disadvantage that the ground truth is