30/3/2001

This directory contains three gzipped files "scc_soft3.0b.tar.gz", 
"CypData.tar.gz", and CelGene.tar.gz.  Individual data files are also stored in
the ./CypData directory for convenience of non-UNIX users.

Warning:
./table/mdm_mtx is no longer compatible with the previous version.  Please use 
the new file packed here, or create it by running makmdm.

Scc-soft collects programs developed by Osamu Gotoh at Saitama Cancer
Center Research Institute for sequence alignment and phylogenetic
reconstruction.  The new release of "aln" performs pairwise alignment
between (groups of) nucleotide sequences, (groups of) protein sequences or
between a DNA sequence and a (group of) protein sequence.  With the last
setting, "aln" can be used to predict eukaryotic gene structures based on
sequence homology.  Likewise, new "prrn" and "phyln" combine respective
previous versions for protein sequences and nucleotide sequences.   For more
detailed information, see the files in ./doc directory.

CypData contains alignments and trees of some of the cytochrome P450
(CYP) family proteins.  C. elegans sequences were predicted from genomic
DNA sequences by using "aln".  

CelGene collects a set of C. elegans gene structures verified by comparison
of genomic DNA sequences and cDNA sequences.  

All materials in this directory may be freely distributed for academic uses.
For commercial purposes, contact the address below.

Contact address:

Osamu Gotoh, Ph.D.

Computational Biology Research Center
National Institute of Advanced Industrial Sciences and Technology

2-41-6 Aomi, Koutou-ku, Tokyo 135-0064, Japan
Phone: +81-3-3599-8040  Fax +81-3-3599-8081
E-mail: o.gotoh@aist.go.jp