Discrimination of membrane proteins based on structure and function

Prediction of membrane spanning segments in alpha-helical and beta-barrel membrane proteins

Recognition of protein folds

Prediction of secondary and tertiary structures in globular proteins

Conformational stability of proteins and nucleic acids

Identification of important residues for protein stability and function

Extreme stability of thermophilic proteins

Prediction of protein stablity upon amino acid substitutions

Medium and Long Range Interactions in Gobular Proteins

Development of novel parameters/methods for understanding/predicting protein folding rates

Development of thermodynamic and functional databases for proteins and interactions

Structural analysis of proteins and their interactions

Elastic characters of DNA/RNA and importance to binding specificity

Computer simulation of protein-DNA interactions

Recognition mechanism for protein-protein, protein-nucleic acid, protein-carbohydrate and protein-ligand interactions